https://www.probiometrics.com/blog daily 0.75 2023-10-18 https://www.probiometrics.com/blog/a-unique-insight-into-diabetes monthly 0.5 2023-10-18 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/e7394b9c-7a09-49ab-a074-1b89540ae0f5/Diabetes.png Healthy Progress - A unique insight into diabetes - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.probiometrics.com/blog/the-new-sleep-labs monthly 0.5 2023-10-18 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/6bd509a1-e4c9-40e5-85e7-8f5e259494cd/Sleep+Cartoon.png Healthy Progress - A breakthrough in sleep analysis - Clinical level sleep disorder analysis can be tricky. For starters the subject needs to be able to get to sleep, a process not especially helped along by the abundance of machines, wires and sticky patches involved. Nor by the fact that you will almost certainly be in a strange bed in unfamiliar surroundings. Our latest research using ProCVT means all of that is about to get a lot easier. https://www.probiometrics.com/blog/parasympathetic-hard-to-pronounce-easy-to-measure monthly 0.5 2022-11-04 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/4397365e-3fe6-47b2-bcdd-3960bf38e3bd/Screenshot+2022-11-01+at+12.04.42.png Healthy Progress - Parasympathetic. Hard to say, easy to measure. - As this brief interview with Financial Freedom Today at the Future Innovation Summit in Dubai clearly shows, “parasympathetic” can be a bit of a mouthful when you’re thrust in front of a camera. So why even mention it? Is it something we need to measure at all? And what tortuous process would you have to go through to gather the data? https://www.probiometrics.com/blog/category/sleep+stages monthly 0.5 https://www.probiometrics.com/blog/category/Sleep+study monthly 0.5 https://www.probiometrics.com/blog/category/sleep+analysis monthly 0.5 https://www.probiometrics.com/blog/tag/cvt monthly 0.5 https://www.probiometrics.com/blog/tag/hypnogram monthly 0.5 https://www.probiometrics.com/blog/tag/CVT monthly 0.5 https://www.probiometrics.com/blog/tag/stress monthly 0.5 https://www.probiometrics.com/blog/tag/cardiovascular+disease monthly 0.5 https://www.probiometrics.com/blog/tag/autonomic monthly 0.5 https://www.probiometrics.com/blog/tag/health+monitoring monthly 0.5 https://www.probiometrics.com/blog/tag/hypnograph monthly 0.5 https://www.probiometrics.com/blog/tag/sleep+stages monthly 0.5 https://www.probiometrics.com/blog/tag/EEG monthly 0.5 https://www.probiometrics.com/blog/tag/health+%26+wellbeing monthly 0.5 https://www.probiometrics.com/blog/tag/cardiac+vagal+tone monthly 0.5 https://www.probiometrics.com/blog/tag/sleep+study monthly 0.5 https://www.probiometrics.com/blog/tag/parasympathetic monthly 0.5 https://www.probiometrics.com/blog/tag/polysomnography monthly 0.5 https://www.probiometrics.com/blog/tag/REM monthly 0.5 https://www.probiometrics.com/blog/tag/diabetes monthly 0.5 https://www.probiometrics.com/blog/tag/sleep+analysis monthly 0.5 https://www.probiometrics.com/customersectors daily 0.75 2022-05-03 https://www.probiometrics.com/customersectors/blog-post-title-one-2d6be monthly 0.5 2021-06-30 https://www.probiometrics.com/customersectors/blog-post-title-four-acx43 monthly 0.5 2021-06-30 https://www.probiometrics.com/customersectors/blog-post-title-two-jw3r9 monthly 0.5 2021-06-30 https://www.probiometrics.com/customersectors/blog-post-title-three-6t79r monthly 0.5 2021-06-30 https://www.probiometrics.com/customersectors/blog-post-title-four-acx43-6n6ge-hz4jn monthly 0.5 2021-06-30 https://www.probiometrics.com/customersectors/blog-post-title-four-acx43-6n6ge monthly 0.5 2021-06-30 https://www.probiometrics.com/customersectors/sports-analytics monthly 0.5 2021-06-30 https://www.probiometrics.com/customersectors/research monthly 0.5 2022-05-03 https://www.probiometrics.com/home daily 1.0 2022-11-10 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612540980999-SBJXH7MGJP0DZEGNK3EV/ProCVT-Logo-BB-Reg.png Home - Effortless, accurate and scalable remote health monitoring https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1623334461223-O8W5B5ZEE5UASXI83D48/WhatsApp+Image+2021-06-10+at+14.10.37.jpeg Home ProCVT Prototype in Action https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1588670019395-BZ0P07KJAVKLONMIMK2E/image-asset.jpeg Home - Accuracy The best time for measuring vital signs is at rest or whilst you’re asleep in bed ProCVT captures a high resolution ECG and surface temperature, from which it effortlessly delivers a real time output of four key "vital signs”: respiration rate, body temperature, heart rate and CVT, enabling detailed cardiovascular analysis. Because this data is captured over long periods, while you sleep or while you are at rest, variations caused by external factors (eg. physical exertion, ambient temperature changes, stress) are minimised. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612534153128-QVB4TLVKZFE3V0OYA7WR/Old%2Bvagus%2Bnerve%2Bimage.jpg Home https://www.probiometrics.com/technology daily 0.75 2022-05-03 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612708209310-LRLRSOSRT87S3T7J6B9C/cloud+server.png Technology - PBM Cloud Based Systems PBM’s cloud based systems are responsible for processing ECG metadata into vital signs data. Respiration rate measurement is derived by implementation of state of the art algorithms which combine baseline ECG signal and QRS complex amplitudes. Temperature measurements through three layers of material have been shown to correlate with an armpit reading. At the core of our systems is the implementation of Dr Peter Julu’s CVT algorithm. This algorithm is only suitable for perfectly clean clinical data, so in order to deploy CVT to non-clinical settings PBM systems need to ‘clean’ the ECG data of artefacts. Complex data cleansing software to identifies and potentially fix artefacts to ensure that a continuous, consistent and smooth output was obtained from the algorithm. As part of this process the system assigns a confidence score to each reading so as a measure of the input data quality. As well as processing the CVT data, PBM systems allow CVT data that is being streamed from ProCVT to be combined with other streams and viewed remotely on another mobile device. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612704967765-E11PL9TEFGTRL4TVIYJC/Screenshot+2021-02-07+at+13.23.28.png Technology - Current data capture technology While the sheet monitor is being developed, PBM is still able to deliver its valuable health and wellbeing insights using high resolution ECG data taken from a digital micro-sensor worn on the chest. Data is sent to PBM’s servers where heart rate, respiration rate and CVT is calculated and visible in real time via a mobile app, or analysed retrospectively on the web app The Bittium device is a 3 or 1 channel ECG: IP67 waterproof ECG sampling 1000 Hz 3D acceleration sampling up to 100Hz Memory capacity up to 180 days Recharging time: ca. 1.5 hours Battery life up to 8 days https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612705172843-TBKLNCEZMNSKKM3PGNG3/hand+holding+phone.png Technology https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612704775649-HDP8A79H3ZTAOFOJ4K1Q/Bittium+device.png Technology https://www.probiometrics.com/research daily 0.75 2022-05-25 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/13df5e62-bd66-4d09-99cd-017839ca3826/phone+app+in+bed.jpg Research - Sleep Quality An initial pilot study by Dr Peter Julu (Consultant Autonomic Neurophysiologist - Queen Mary’s Hospital), Dr Shane Delamont (Consultant Neurologist and Honorary Lecturer at King’s College) and Dr Guy Leschziner (world renowned expert on sleep and head of the Sleep Disorders Clinic Guy’s & St Thomas’ Hospital) has proved ProCVT’s ability to measure arousal suppression during sleep: “The current results from the New Zealand study strongly suggests that CVT can be used to indicate the strengths of arousal inhibition during sleep. The strength of arousal inhibition is turned up probably to its maximum possible level when the body requires rest and it is gradually reduced to its lowest level during deep sleep. This process is repeated whenever arousal rises to a level that is not compatible with deep sleep either during the ongoing sleep or whenever the body still requires rest.” Dr Peter Julu. This research has demonstrated CVT’s unique capability to objectively measure brainstem activity, opening up the potential to make clinical level measurements of a person’s sleep effortlessly and over time. The accuracy of ProCVT significantly exceeds that of existing wrist based wearables, showing a 98% correlation with slow wave sleep patterns captured from a brain wave monitor (EEG). For the first time there will be a high correlation between a sleep tracker user's sleep experience and the actual output of the tracker. Some 49% of American adults are concerned about developing a degenerative brain disease such as Alzhiemers, and 48% of the same population are aware that the most effective prevention strategy is improved sleep quality. In reality the major component of sleep architecture which prevents the development of degenerative brain disease is deep sleep. ProCVT’s is capable of measuring the duration of deep sleep with an accuracy that until now has been limited to brainwave monitors that need to worn. This combination unlocks the possibility of tracking the effect of standard interventions, which ones work and to what degree. It would be beneficial to gamify a user’s results, encouraging them when they do well and warning them when things are going in the wrong direction. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612801713065-6EI7XCW9ONEHHDNVX79R/Diabetes.png Research - Diabetes Management Studies have already been published that have shown CVT is an effective screening tool for Cardiovascular Autonomic Neuropathy, which is a widespread (62% of type 2 diabetics), poorly detected and potentially fatal condition associated with diabetes. As a result the International Autonomic Group (IAG) has recently been set up comprising the Aalborg University Hospital in Denmark, Queen Mary’s University Hospital in London and ProBiometrics. The first research program being carried out by the IAG culminates in an international multicenter intervention study that will leverage ProCVT to measure overnight glucose spikes that will ultimately lead to the accurate titration of the latest diabetes medication, improving effectiveness of such treatments whilst significantly reducing costs. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612801537242-FYYFGFWY3T5YXMRZY84E/Anasthesiology.png Research - Anaesthesiology A leading professor of anaesthesiology has identified a potential benefit of ProCVT’s monitoring of ECG and respiration rate in operating theatres, due to absence of wires/leads, the reduction in set-up time and inconvenience when moving patients, and the reduction in post operative vital signs monitoring time. It has also been shown that a real time monitoring of CVT will allows surgeons to actually see what hurts the patient, reducing complications and improving postoperative recovery. Trial proposal has been submitted to PBM and is being reviewed. https://www.probiometrics.com/sleep daily 0.75 2021-02-09 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1588834982135-XB6LLKYDBR1UK3UTT9HJ/Screenshot%2B%252810%2529.jpg Sleep - Biofeedback By witnessing your brain stem controlling the vagus drive throughout your sleep, you can learn the impact of your habits, nutrition, stress and lifestyle on your sleep patterns and ability to recover https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1588850807032-0DHUUI3RB13JRFDAY17Q/Nightly+CVT+assessment.png Sleep - Develop insights into your sleep patterns Are you refreshed and ready to go upon waking? Or still deep into recovery when morning comes around? In the graphs opposite Subject 2 (in Blue) shows a wedge shape pattern, with increasing levels of recovery peaking just before the alarm call. She typically awakes groggy and tired compare to Subject 1 (in Green) who achieves deepest recovery much earlier in the night, feeling refreshed upon waking https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612782964675-7BRV6PUOZ6M9KC57VFMU/Screenshot+2021-02-08+at+11.15.15.png Sleep - A limited number of clients will be coached directly by our Director of Human Performance, Ian Wynne Ian is a successful Olympic athlete with over 20 years of experience exploring and developing human potential. He has spent 9 years in elite coaching with world-class athletes, is an Independent Performance Consultant, and has extensive knowledge and practical experience of applying CVT within the field of human performance and research. Ian has applied this knowledge across a diverse range of organisations such as the Wates Group, Lego, AA Drivetech, Goldsmiths University and with individuals seeking to perform at their peak abilities including Olympic athletes and company CEO’s, directors and project managers. https://www.probiometrics.com/personal-performance daily 0.75 2022-05-25 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1588854957912-7QQSZISWJPNXV6BLUUO0/33hr%2BCVT%2Bcontinuous.jpg Personal performance - Your heart knows best For every heart beat, ProCVT captures and records the exact amount of vagal tone on a simple linear scale which is standardised across everyone. This unique measure allows you to see exactly how much vagal break is being applied to your heart on a beat by beat basis, identifying patterns of stress, strain and recovery. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1588862900260-ZVS0A6SNTACJL9GUR613/Ian%252BWynne Personal performance https://www.probiometrics.com/corporate daily 0.75 2022-05-25 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1588854957912-7QQSZISWJPNXV6BLUUO0/33hr%2BCVT%2Bcontinuous.jpg Corporate - Your heart knows best For every heart beat, ProCVT captures and records the exact amount of vagal tone on a simple linear scale which is standardised across everyone. This unique measure allows you to see exactly how much vagal break is being applied to your heart on a beat by beat basis, identifying patterns of stress, strain and recovery. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1588862900260-ZVS0A6SNTACJL9GUR613/Ian%252BWynne Corporate https://www.probiometrics.com/privacy-policy daily 0.75 2021-02-08 https://www.probiometrics.com/terms-of-service daily 0.75 2021-02-08 https://www.probiometrics.com/the-team daily 0.75 2026-03-23 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/8f5cb74e-7717-441c-b44c-93f5b16bc94f/IMG_8590.jpeg The Team DR MARTIN OEHLER, FOUNDER & CEO https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1589036421161-BERWMBQEGUFVP2TC37MJ/Kerstin+Sallows.png The Team KERSTIN SALLOWS, FOUNDER & EXECUTIVE CHAIR https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/2c4cec0d-5d19-44ed-b905-6db3897f5c41/Business+Profile.jpeg The Team KEITH DAVIDSON, COO AND DIRECTOR OF MARKETING https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1614251878905-H9FW7CFF1XWOEK6QBN91/Screenshot+2021-02-25+at+11.17.53.png The Team IAN WYNNE, DIRECTOR OF RESEARCH & HUMAN PERFORMANCE https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612711084080-FIBJDIDN214OERS1E57M/Screenshot+2021-02-07+at+15.09.23.png The Team - DR PETER JULU (MBChB, MSc, PhD, FPhysiol, FRCP) Leading world expert in autonomic neurophysiology. He practices clinically and carries out cutting-edge clinical neurophysiological research, both internationally and in the UK. Dr Julu is the inventor of the NeuroScope, a machine for autonomic assessment and monitoring of brainstem functions https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612711099574-WMU7B9XYG44JCZ18VQIT/Screenshot+2021-02-07+at+15.12.40.png The Team - PROFESSOR MELVIN LOBO (MBChB PhD FRCP FBHS FESC FACC) A pioneering cardiovascular specialist based in London. Considered a global thought leader for his work as a specialist in all forms of blood pressure disorders. He has been involved in a number of important clinical studies of device-based therapies for these conditions https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1612711188995-V4I1E96XKVET0UVI92CI/Dr+Shane+Delamont.jpeg The Team - DR SHANE DELAMONT (MB BS, MD, FRACP, FRCP) Consultant Neurologist with specialist interest in the diagnosis and management of epilepsy, syncope and seizure-like attacks. He specialised in epilepsy and cardiovascular autonomic function before his appointment at King’s as consultant neurologist. He is also honorary senior lecturer at King’s College London https://www.probiometrics.com/collaborations daily 0.75 2025-10-13 https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/4c08c5fe-6a3b-423d-9c77-4412132bd8b4/Screenshot+2025-10-13+at+10.40.00.png Collaborations - William Harvey Research Foundation PBM has been working with key personnel at Queen Mary University London and the William Harvey Clinical Research Centre on a proposal to establish a “Vital Signs Hub” (ie. A single point of biometric data collation and analysis) for the NHS. Having now seen the Sensor-Sheets in action, this team believes ProCVT could be a key part of the proposal and could be successfully deployed within the NHS. Key stakeholders in the project are Prof Aziz, Prof Anthony Mathur (who has agreed to be the Principle Investigator and final decision-maker on grant funding), and Naveed Sultan. The proposal has also been shared with Prof. Sir Mark Caulfield who has offered his tacit support. The NHS Health Economics Unit will quantify the cost savings to support mass adoption within the NHS, and will be involved from the start. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1614177942811-HD7LBRESQVVOJSUY17ZJ/Screenshot+2021-02-24+at+14.45.28.png Collaborations - University of Aalborg A feasibility study of CVT, captured using the prototype sensor-sheets, as a new screening tool for Cardiovascular Autonomic Neuropathy (CAN) was carried out at the University of Aalborg in Denmark. The study was funded by Novo Nordisk. The resulting paper is authored by Maria Bitsch Poulsen and Prof. Christina Brock, and will be published in November 2025. A total of 164 recordings were obtained via the prototype sensor-sheets, with an average of 93% of each recording classified as very high signal quality before artefact removal. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1614180800726-G1GTECE87VJ2V152A30L/Screenshot+2021-02-24+at+15.33.02.png Collaborations - Barwon Infant Study The Barwon Infant Study is a major birth cohort study that has been running since 2010 out of the Child Health Research Unit (CHRU) at Barwon Health and in collaboration with the Murdoch Children’s Research Institute (MCRI) and Deakin University, Australia. It has been using ProCVT measurements from the cohort of 1000 children as part of their monitoring of developmental progress. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1628582207968-RHY8LWIX88MQDPQRPRMM/image-asset.png Collaborations - Coventry University ProBiometrics is collaborating with the Centre for Intelligent Healthcare and the Data Driven Research & Innovation (DDRI) Programme, both based at Coventry University. Academic working groups have been established including leading academics in the field of intelligent healthcare development, clinical care innovation, and health technology assessment in order to guide and execute relevant ongoing clinical trials for the elderly residential care home and hospital sectors. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1623845580517-ANTKKUR69B4T2IG3YTXV/LUDUM+Stacked-Coral+RGB.png Collaborations - Endurance Sports Research Ltd Under the brand name Ludum, ESR Ltd is working with PBM to enhance their “morning monitoring” module, which provides insight into an athlete’s current state of readiness. Using ProCVT it is expected that this “training load response” can be measured objectively for the first time, and ESR Ltd has already commenced trials with elite athletes to verify this. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1614181641245-W9QHJTR050CYZ19IUJ74/Screenshot+2021-02-24+at+15.47.09.png Collaborations - Wates Group PBM was commissioned by Wates Construction to conduct an investigation into the stress, sleep quality and recovery levels of four of its project managers. The project was overseen by John Dunne, Wates Group’s Director of HSEQ and Sustainability: “We often say our front line managers are under pressure; but how much pressure, when? All the time? And what can we do about it? Ian and the ProBiometrics team allowed us to gain a greater insight into the relentless pressure our key decision makers were under and, more importantly, recommended improvement programmes tailored to the individual’s needs.” Wates have now stated their interest in trialling the prototype sheet monitor device with ten pre-selected employees. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1614181360819-GFSYQDORKD2T6RG4S1BJ/Screenshot+2021-02-24+at+15.42.12.png Collaborations - Automobile Association A study was conducted by the Automobile Association’s DriveTech division using ProCVT’s real time measurement of parasympathetic nervous system activity in order to compare the differences in engagement and stress between experienced versus inexperienced drivers. The subsequent video shows a live CVT readout on the drivers. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1614181439992-80XSWQJWWYD9YTVLY3KP/Screenshot+2021-02-24+at+15.43.42.png Collaborations - Lego In collaboration with researchers at Goldsmiths, University of London, and using ProCVT, the LEGO Group measured the effect of different kinds of play on the physical, social, cognitive, creative and emotional skills of five participant volunteers. The Lego study and ProCVT were featured on BBC Click. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1614180887785-D7S2Q5DC3KVDMY8KJGWG/Screenshot+2021-02-24+at+15.34.31.png Collaborations - Deep Space Predictive Research Group Deep Space Predictive Group is using ProCVT to help maximise astronaut performance during long duration space missions. It is a core part of their proposal to NASA for its HERA mission. DSPG recognises the centrality of emotion in health, decision making, performance and group cohesion, especially in the context of extreme isolation. CVT is the anchor for linking these domains in a meaningful and scientifically precise way for monitoring and support. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1614179390592-HUO41ZZO6ZXXAG8PXE4F/Screenshot+2021-02-24+at+15.09.35.png Collaborations - Silent Mode The stress management product manufacturer is using ProCVT to guide product development, and with a view to further collaboration with PBM in the future. Silent Mode recognises CVT as a core part of measuring health and wellbeing, and monitoring the efficacy of interventions. https://images.squarespace-cdn.com/content/v1/5eb07e7096a87a08367482de/1614185834352-9RJ9DHTPBCA14XVAPGDU/Screenshot+2021-02-24+at+16.56.01.png Collaborations - Vicky Thornley 2016 Rio Olympic silver medalist Vicky Thornley used ProCVT to monitor sleep and recovery through her winter training: “As an Olympic athlete I am always looking how I can improve my training and recovery, to lead to a better performance. CVT feedback has been a great additional monitoring tool, providing a clear and objective measure. I use it day to day, as well as observing the effects of my training programme over longer periods.” https://www.probiometrics.com/future-innovation-summit-2022 daily 0.75 2023-10-24